Linked Life Data

17150725

Source:http://linkedlifedata.com/resource/pubmed/id/17150725

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
49
pubmed:dateCreated
2006-12-7
pubmed:abstractText
We analyzed the coordination structure of G-quadruplexed DNA-heme complex which exhibits remarkably similar spectroscopic characters to hemoprotein such as myoglobin. We found that some exogenous ligands can be accommodated at the 6th coordination site of heme in the G-quadruplexed DNA-heme complex with a DNA base coordinated to the 5th site. The G-quadruplexed DNA-hemin complex is expected to play a role as a novel DNAzyme. These findings provide novel insights into molecular design for creating artificial heme enzymes using spontaneous assembly between G-quadruplexed DNA and heme.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1746-8272
pubmed:author
pubmed:issnType
Electronic
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
245-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Structural and functional characterization of novel G-quadruplexed DNA-heme coordination complex.
pubmed:affiliation
Department of Chemistry, University of Tsukuba, Tsukuba 305-8577, Japan.
pubmed:publicationType
Journal Article