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pubmed-article:17150655pubmed:dateCreated2006-12-7lld:pubmed
pubmed-article:17150655pubmed:abstractTextFor the purpose of developing optimal neoceptor-neoagonist pair, 3'-ureidoadenosine derivatives were synthesized. Among compounds tested, 2-chloro-3'-ureido-N6-(3-iodobenzyl)adenosine (10b) showed the best binding affinity (Ki = 0.20 microM) at the H272E mutant A3 AR, but was inactive at the natural A3 AR.lld:pubmed
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pubmed-article:17150655pubmed:authorpubmed-author:KimHea OkHOlld:pubmed
pubmed-article:17150655pubmed:authorpubmed-author:JeongLak...lld:pubmed
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pubmed-article:17150655pubmed:authorpubmed-author:ChunMoon...lld:pubmed
pubmed-article:17150655pubmed:authorpubmed-author:LeeKang ManKMlld:pubmed
pubmed-article:17150655pubmed:authorpubmed-author:KimAe YilAYlld:pubmed
pubmed-article:17150655pubmed:authorpubmed-author:KimMyoung...lld:pubmed
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pubmed-article:17150655pubmed:pagination105-6lld:pubmed
pubmed-article:17150655pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:17150655pubmed:articleTitleSynthesis of 3'-ureidoadenosines and their high binding affinity at the mutant A3 adenosine receptor.lld:pubmed
pubmed-article:17150655pubmed:affiliationLaboratory of Medicinal Chemistry, College of Pharmacy, Ewha Womans University, Seoul 120-750, Korea.lld:pubmed
pubmed-article:17150655pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17150655pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed