Linked Life Data

17150655

Source:http://linkedlifedata.com/resource/pubmed/id/17150655

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
49
pubmed:dateCreated
2006-12-7
pubmed:abstractText
For the purpose of developing optimal neoceptor-neoagonist pair, 3'-ureidoadenosine derivatives were synthesized. Among compounds tested, 2-chloro-3'-ureido-N6-(3-iodobenzyl)adenosine (10b) showed the best binding affinity (Ki = 0.20 microM) at the H272E mutant A3 AR, but was inactive at the natural A3 AR.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1746-8272
pubmed:author
pubmed:issnType
Electronic
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-6
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Synthesis of 3'-ureidoadenosines and their high binding affinity at the mutant A3 adenosine receptor.
pubmed:affiliation
Laboratory of Medicinal Chemistry, College of Pharmacy, Ewha Womans University, Seoul 120-750, Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't