Source:http://linkedlifedata.com/resource/pubmed/id/17150580
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
48
|
| pubmed:dateCreated |
2006-12-7
|
| pubmed:abstractText |
We attempted to utilize in vitro selection techniques to develop modified DNA aptamers that are specific for DNA secondary structure including a single-mismatch base pair. For the selection, two kinds of random modified DNA library were prepared by an enzymatic method using modified 2'-deoxynucleoside 5'-triphosphates and KOD Dash DNA polymerase: one library consists of modified DNA including amino functionality and another consists of modified DNA including both hydroxypropynyl and guanidium functionalities.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1746-8272
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
265-6
|
| pubmed:dateRevised |
2007-9-19
|
| pubmed:meshHeading |
pubmed-meshheading:17150580-Aptamers, Nucleotide,
pubmed-meshheading:17150580-Base Pair Mismatch,
pubmed-meshheading:17150580-Base Sequence,
pubmed-meshheading:17150580-DNA,
pubmed-meshheading:17150580-DNA-Directed DNA Polymerase,
pubmed-meshheading:17150580-Gene Library,
pubmed-meshheading:17150580-Molecular Sequence Data,
pubmed-meshheading:17150580-Nucleic Acid Conformation,
pubmed-meshheading:17150580-SELEX Aptamer Technique
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
Screening of modified DNA aptamers that recognize DNA secondary structure.
|
| pubmed:affiliation |
Department of Applied Chemistry, Gunma University, Kiryu, Gunma 376-8515, Japan.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|