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pubmed-article:17149577pubmed:abstractTextVarious radiotherapy (RT) schedules are used worldwide for metastatic spinal cord compression (MSCC). Every treatment session may cause discomfort to the mostly debilitated patients. A short overall treatment time appears beneficial, especially for MSCC patients with an extremely poor survival such as colorectal cancer patients. This study evaluates whether short-course RT (1 x 8 Gy given in 1 day, 5 x 4 Gy given in 1 week) is as effective as long-course RT (10 x 3 Gy given in 2 weeks, 15 x 2.5 Gy given in 3 weeks, 20 x 2 Gy given in 4 weeks) and whether higher doses per fraction (more cell kill) and shorter overall treatment time (less repopulation) can compensate for lower total doses.lld:pubmed
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pubmed-article:17149577pubmed:year2006lld:pubmed
pubmed-article:17149577pubmed:articleTitleIs short-course radiotherapy with high doses per fraction the appropriate regimen for metastatic spinal cord compression in colorectal cancer patients?lld:pubmed
pubmed-article:17149577pubmed:affiliationDepartment of Radiation Oncology, University Hospital Schleswig Holstein, Campus Luebeck, Luebeck, Germany. Rades.Dirk@gmx.netlld:pubmed
pubmed-article:17149577pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17149577pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:17149577pubmed:publicationTypeMulticenter Studylld:pubmed
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