Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2006-12-6
pubmed:abstractText
Various radiotherapy (RT) schedules are used worldwide for metastatic spinal cord compression (MSCC). Every treatment session may cause discomfort to the mostly debilitated patients. A short overall treatment time appears beneficial, especially for MSCC patients with an extremely poor survival such as colorectal cancer patients. This study evaluates whether short-course RT (1 x 8 Gy given in 1 day, 5 x 4 Gy given in 1 week) is as effective as long-course RT (10 x 3 Gy given in 2 weeks, 15 x 2.5 Gy given in 3 weeks, 20 x 2 Gy given in 4 weeks) and whether higher doses per fraction (more cell kill) and shorter overall treatment time (less repopulation) can compensate for lower total doses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0179-7158
pubmed:author
pubmed:issnType
Print
pubmed:volume
182
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
708-12
pubmed:meshHeading
pubmed-meshheading:17149577-Cell Survival, pubmed-meshheading:17149577-Colorectal Neoplasms, pubmed-meshheading:17149577-Dose Fractionation, pubmed-meshheading:17149577-Female, pubmed-meshheading:17149577-Humans, pubmed-meshheading:17149577-Magnetic Resonance Imaging, pubmed-meshheading:17149577-Male, pubmed-meshheading:17149577-Middle Aged, pubmed-meshheading:17149577-Neurologic Examination, pubmed-meshheading:17149577-Palliative Care, pubmed-meshheading:17149577-Photons, pubmed-meshheading:17149577-Prognosis, pubmed-meshheading:17149577-Radiotherapy Dosage, pubmed-meshheading:17149577-Radiotherapy Planning, Computer-Assisted, pubmed-meshheading:17149577-Retrospective Studies, pubmed-meshheading:17149577-Spinal Cord Compression, pubmed-meshheading:17149577-Spinal Neoplasms, pubmed-meshheading:17149577-Survival Rate, pubmed-meshheading:17149577-Tomography, X-Ray Computed
pubmed:year
2006
pubmed:articleTitle
Is short-course radiotherapy with high doses per fraction the appropriate regimen for metastatic spinal cord compression in colorectal cancer patients?
pubmed:affiliation
Department of Radiation Oncology, University Hospital Schleswig Holstein, Campus Luebeck, Luebeck, Germany. Rades.Dirk@gmx.net
pubmed:publicationType
Journal Article, Comparative Study, Multicenter Study