Source:http://linkedlifedata.com/resource/pubmed/id/17149577
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2006-12-6
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pubmed:abstractText |
Various radiotherapy (RT) schedules are used worldwide for metastatic spinal cord compression (MSCC). Every treatment session may cause discomfort to the mostly debilitated patients. A short overall treatment time appears beneficial, especially for MSCC patients with an extremely poor survival such as colorectal cancer patients. This study evaluates whether short-course RT (1 x 8 Gy given in 1 day, 5 x 4 Gy given in 1 week) is as effective as long-course RT (10 x 3 Gy given in 2 weeks, 15 x 2.5 Gy given in 3 weeks, 20 x 2 Gy given in 4 weeks) and whether higher doses per fraction (more cell kill) and shorter overall treatment time (less repopulation) can compensate for lower total doses.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0179-7158
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
182
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
708-12
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pubmed:meshHeading |
pubmed-meshheading:17149577-Cell Survival,
pubmed-meshheading:17149577-Colorectal Neoplasms,
pubmed-meshheading:17149577-Dose Fractionation,
pubmed-meshheading:17149577-Female,
pubmed-meshheading:17149577-Humans,
pubmed-meshheading:17149577-Magnetic Resonance Imaging,
pubmed-meshheading:17149577-Male,
pubmed-meshheading:17149577-Middle Aged,
pubmed-meshheading:17149577-Neurologic Examination,
pubmed-meshheading:17149577-Palliative Care,
pubmed-meshheading:17149577-Photons,
pubmed-meshheading:17149577-Prognosis,
pubmed-meshheading:17149577-Radiotherapy Dosage,
pubmed-meshheading:17149577-Radiotherapy Planning, Computer-Assisted,
pubmed-meshheading:17149577-Retrospective Studies,
pubmed-meshheading:17149577-Spinal Cord Compression,
pubmed-meshheading:17149577-Spinal Neoplasms,
pubmed-meshheading:17149577-Survival Rate,
pubmed-meshheading:17149577-Tomography, X-Ray Computed
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pubmed:year |
2006
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pubmed:articleTitle |
Is short-course radiotherapy with high doses per fraction the appropriate regimen for metastatic spinal cord compression in colorectal cancer patients?
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pubmed:affiliation |
Department of Radiation Oncology, University Hospital Schleswig Holstein, Campus Luebeck, Luebeck, Germany. Rades.Dirk@gmx.net
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pubmed:publicationType |
Journal Article,
Comparative Study,
Multicenter Study
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