rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2006-12-6
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pubmed:abstractText |
Cell communication in the lens is critical for the life-long homeostasis of this tissue. Abundant gap junctions and cell-cell fusions are reported to be indispensable to the metabolic requirements and optical properties of the highly interconnected syncytial lens tissue. The expression of the recently characterized Panx1 and Panx2 gap junction proteins in the lens is, therefore, rather intriguing. Co-expression of pannexins and abundant connexins in the lens suggests that the two gap junction protein families have distinct roles in cell communication.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1417-26
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17149368-Animals,
pubmed-meshheading:17149368-Connexins,
pubmed-meshheading:17149368-Erythrocytes,
pubmed-meshheading:17149368-HeLa Cells,
pubmed-meshheading:17149368-Humans,
pubmed-meshheading:17149368-Immunohistochemistry,
pubmed-meshheading:17149368-Lens, Crystalline,
pubmed-meshheading:17149368-Mice,
pubmed-meshheading:17149368-Mice, Inbred C57BL,
pubmed-meshheading:17149368-Nerve Tissue Proteins,
pubmed-meshheading:17149368-RNA, Messenger,
pubmed-meshheading:17149368-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17149368-Staining and Labeling
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pubmed:year |
2006
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pubmed:articleTitle |
Molecular characterization of pannexins in the lens.
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pubmed:affiliation |
Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. gdvoriantchikova@med.miami.edu <gdvoriantchikova@med.miami.edu>
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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