Linked Life Data

17148848

Source:http://linkedlifedata.com/resource/pubmed/id/17148848

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-12-6
pubmed:abstractText
Studies were carried out on stroke-prone spontaneously hypertensive rats (SHRSP) to determine the cardiovascular effects of a traditional medicine extracted from the fungus Fuscoporia obliqua. The rats received either a hot-water extract of Fuscoporia or tap water for 60 days. Heart rate and blood pressure were measured in the tail and venous blood was analyzed for glycated hemoglobin (HbA1c) and leukocyte number. Sections of the left ventricular wall were stained for alkaline phosphatase and dipeptidylpeptidase IV to distinguish the arteriolar from the venular portions of the capillaries. Capillary to myocyte ratio (C:M ratio) was also measured. Treated rats showed a significant decrease in arterial pressure, a mild increase in leukocyte and a trend towards a decrease in HbA1c. There was a trend towards an increase in total capillary density in the subendomyocardium accompanied by a decrease in the arteriolar capillary portions. C:M ratio showed no clear change. It is concluded that the hot-water extract of Fuscoporia has beneficial effects on cardiovascular function, hematological status and probably immunological function in SHRSP.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1386-0291
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
491-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Cardiovascular effects produced by a traditional fungal medicine, Fuscoporia obliqua extract, and microvessels in the left ventricular wall of stroke-prone spontaneously hypertensive rat (SHRSP).
pubmed:affiliation
Hokkaido University, Sapporo, Japan. tomkoyamajp@yahoo.co.jp
pubmed:publicationType
Journal Article