|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
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|
pubmed:dateCreated |
2006-12-12
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|
pubmed:abstractText |
The role of c-FLIP in cell motility was investigated using RNA interference. Down-regulation of c-FLIP increased amounts of reactive oxygen species (ROS), while over-expression of c-FLIP produced opposite effect. ROS induced phosphorylation of Akt and impaired cell motility.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1573-6776
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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|
pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
141-7
|
|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
|
|
pubmed:year |
2007
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|
pubmed:articleTitle |
Down-regulation of c-FLIP increases reactive oxygen species, induces phosphorylation of serine/threonine kinase Akt, and impairs motility of cancer cells.
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|
pubmed:affiliation |
School of Biological Sciences, College of Natural Sciences, Kangwon National University, Chunchon, Korea.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
