Source:http://linkedlifedata.com/resource/pubmed/id/17145574
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2006-12-5
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pubmed:abstractText |
A phase II trial evaluating 6% topical miltefosine solution was performed in 12 pretreated patients with cutaneous T-cell lymphoma. Miltefosine (Miltex) was administered for 8 weeks, once per day during the first week then twice every day for seven weeks. Main side effects consisted in moderate to mild pruritus or desquamation in 57 % and 50 % of patients, respectively. No systemic nor biological toxicity was observed. This treatment was administered on an outpatient basis exclusively. The overall response rate was 58 % with a median duration of response of 12 months. Miltefosine is a safe, simple and effective treatment in certain patients with cutaneous T-cell lymphoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1769-6917
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
E115-8
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pubmed:dateRevised |
2011-4-5
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pubmed:meshHeading |
pubmed-meshheading:17145574-Adult,
pubmed-meshheading:17145574-Aged,
pubmed-meshheading:17145574-Antineoplastic Agents,
pubmed-meshheading:17145574-Female,
pubmed-meshheading:17145574-Humans,
pubmed-meshheading:17145574-Lymphoma, T-Cell, Cutaneous,
pubmed-meshheading:17145574-Male,
pubmed-meshheading:17145574-Middle Aged,
pubmed-meshheading:17145574-Phosphorylcholine,
pubmed-meshheading:17145574-Skin Neoplasms
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pubmed:year |
2006
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pubmed:articleTitle |
A phase II trial of miltefosine in patients with cutaneous T-cell lymphoma.
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pubmed:affiliation |
Service d'Hématologie, CH Lyon-Sud, Pierre-Bénite, Laboratoire d'Hématologie, Pavillon E, Hôpital Edouard-Herriot, 5 place d'Arsonval, 69003 Lyon Cedex 03, France. charles.dumontet@chu-lyon.fr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
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