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pubmed-article:17143192pubmed:abstractTextBeta-blockers are widely used and effective for treating hypertension, acute myocardial infarction (MI) and heart failure, but they present side-effects mainly due to antagonism of beta2-adrenergic receptor (AR). Currently available beta-blockers are at best selective but not specific for beta1 or beta2-AR.lld:pubmed
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pubmed-article:17143192pubmed:articleTitleSpecific beta1-adrenergic receptor silencing with small interfering RNA lowers high blood pressure and improves cardiac function in myocardial ischemia.lld:pubmed
pubmed-article:17143192pubmed:affiliationChildren's Research Institute, Department of Pediatrics, University of South Florida, Saint Petersburg, FL 33701, USA.lld:pubmed
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