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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-1-18
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pubmed:abstractText |
Chemokines and their receptors are crucially involved in the development of atherosclerotic lesions by directing monocyte and T cell recruitment. The CC-chemokine receptors 1 (CCR1) and 5 (CCR5) expressed on these cells bind chemokines implicated in atherosclerosis, namely CCL5/RANTES. Although general blockade of CCL5 receptors reduces atherosclerosis, specific roles of CCR1 and CCR5 have not been unequivocally determined.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/CCR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Ccr1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, Dietary,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/GATA3 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/GATA3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/HAVCR2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR1,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR5,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Chemokine,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Virus
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1524-4636
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pubmed:author |
pubmed-author:ArnaudClaireC,
pubmed-author:BidzhekovKirilK,
pubmed-author:BraunersreutherVincentV,
pubmed-author:BurgerFabienneF,
pubmed-author:LiehnElisa AEA,
pubmed-author:LuckowBrunoB,
pubmed-author:MachFrançoisF,
pubmed-author:PelliGrazianoG,
pubmed-author:ShagdarsurenErdenechimegE,
pubmed-author:SteffensSabineS,
pubmed-author:WeberChristianC,
pubmed-author:ZerneckeAlmaA
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
373-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17138939-Animals,
pubmed-meshheading:17138939-Apolipoproteins E,
pubmed-meshheading:17138939-Atherosclerosis,
pubmed-meshheading:17138939-Carotid Stenosis,
pubmed-meshheading:17138939-Cell Proliferation,
pubmed-meshheading:17138939-Cholesterol, Dietary,
pubmed-meshheading:17138939-Cytokines,
pubmed-meshheading:17138939-Dietary Fats,
pubmed-meshheading:17138939-Female,
pubmed-meshheading:17138939-GATA3 Transcription Factor,
pubmed-meshheading:17138939-Gene Expression Regulation,
pubmed-meshheading:17138939-Interleukin-10,
pubmed-meshheading:17138939-Lymph Nodes,
pubmed-meshheading:17138939-Membrane Proteins,
pubmed-meshheading:17138939-Mice,
pubmed-meshheading:17138939-Mice, Transgenic,
pubmed-meshheading:17138939-Phenotype,
pubmed-meshheading:17138939-RNA, Messenger,
pubmed-meshheading:17138939-Receptors, CCR1,
pubmed-meshheading:17138939-Receptors, CCR5,
pubmed-meshheading:17138939-Receptors, Chemokine,
pubmed-meshheading:17138939-Receptors, Virus,
pubmed-meshheading:17138939-Spleen,
pubmed-meshheading:17138939-Th1 Cells
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pubmed:year |
2007
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pubmed:articleTitle |
Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice.
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pubmed:affiliation |
Division of Cardiology, Foundation for Medical Research, Faculty of Medicine, Geneva University Hospital, Geneva, Switzerland.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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