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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-11-30
pubmed:abstractText
The main function region of the fusion (F) protein gene of 124 strains of Newcastle disease virus isolated from 2002 to 2004 in China was amplified and sequenced for further phylogenetic and residue substitutive analysis. Most of the isolates were classified into genotype VIIc, VIId, VIf, and VIb, while others into genotype IX, III, or II. The genotype IX, a unique genotype which includes strain F48, the first Chinese virulent NDV strain isolated in 1948, were still found inducing sporadic infections in certain areas. Subgenotype VIIc, VIId, and VIIe viruses, which were distributed in clusters in the phylogenetic tree distinct from members of subgenotypes VIIa and VIIb, were responsible for most outbreaks in China and circulated predominantly in China in recent years. Strain NDV03-026, an isolate of the genotype II which was normally lentogenic, was found carrying (112)RRQKRF(117) motif at the cleavage site of F protein as the virulent strain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0077-8923
pubmed:author
pubmed:issnType
Print
pubmed:volume
1081
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
228-39
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Genotyping of Newcastle disease viruses isolated from 2002 to 2004 in China.
pubmed:affiliation
National Reference Laboratory for Newcastle Disease, Animal Quarantine Institute, Ministry of Agriculture, 369 Nanjing Road, Qingdao, P.C. 266032, People's Republic of China. zlwang111@yahoo.com.cn
pubmed:publicationType
Journal Article