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rdf:type |
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lifeskim:mentions |
umls-concept:C0003873,
umls-concept:C0007613,
umls-concept:C0011306,
umls-concept:C0021469,
umls-concept:C0022417,
umls-concept:C0205245,
umls-concept:C0205419,
umls-concept:C0205483,
umls-concept:C0332281,
umls-concept:C0597357,
umls-concept:C1414554,
umls-concept:C1521828,
umls-concept:C1883709
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|
pubmed:issue |
12
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|
pubmed:dateCreated |
2006-12-28
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pubmed:abstractText |
Fcgamma receptors (FcgammaRs) recognize immune complexes (ICs) and coordinate the immune response by modulating the functions of dendritic cells (DCs). The purpose of this study was to unravel the role of the inhibitory FcgammaRIIb in rheumatoid arthritis (RA) by studying the effect of the FCGR2B 695T>C polymorphism on susceptibility to RA, severity of the disease, and DC function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:BarreraPilarP,
pubmed-author:BonviniEzioE,
pubmed-author:CoenenMarieke J HMJ,
pubmed-author:FrankeBarbaraB,
pubmed-author:KoenigScottS,
pubmed-author:NabbeKarin C A MKC,
pubmed-author:RadstakeTimothy R D JTR,
pubmed-author:WelsingPacoP,
pubmed-author:WeninkMark HMH,
pubmed-author:van RielPiet L C MPL,
pubmed-author:van den BergWim BWB
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
3828-37
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pubmed:meshHeading |
pubmed-meshheading:17133580-Antigens, CD,
pubmed-meshheading:17133580-Arthritis, Rheumatoid,
pubmed-meshheading:17133580-Arthrography,
pubmed-meshheading:17133580-Cytokines,
pubmed-meshheading:17133580-Dendritic Cells,
pubmed-meshheading:17133580-Endocytosis,
pubmed-meshheading:17133580-Female,
pubmed-meshheading:17133580-Genetic Predisposition to Disease,
pubmed-meshheading:17133580-Genotype,
pubmed-meshheading:17133580-Humans,
pubmed-meshheading:17133580-Joints,
pubmed-meshheading:17133580-Leukocytes, Mononuclear,
pubmed-meshheading:17133580-Lipopolysaccharides,
pubmed-meshheading:17133580-Male,
pubmed-meshheading:17133580-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:17133580-Receptors, IgG
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pubmed:year |
2006
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pubmed:articleTitle |
The functional variant of the inhibitory Fcgamma receptor IIb (CD32B) is associated with the rate of radiologic joint damage and dendritic cell function in rheumatoid arthritis.
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pubmed:affiliation |
Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands. T.Radstake@reuma.umcn.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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