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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-11-28
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pubmed:abstractText |
Recently, association of a TOR1A(DYT1)/TOR1B risk haplotype with common forms of idiopathic dystonia has been reported in the Icelandic population. Here we report a strong association of two single nucleotide polymorphisms within or in close proximity to the TOR1A 3'UTR, with the lowest p value being 0.000008, in a larger cohort of German and Austrian patients with predominantly focal sporadic dystonia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1526-632X
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pubmed:author |
pubmed-author:AsmusFF,
pubmed-author:BeckersTT,
pubmed-author:EhlingRR,
pubmed-author:GasserTT,
pubmed-author:IlliaRR,
pubmed-author:KammCC,
pubmed-author:MayerPP,
pubmed-author:MuellerJ CJC,
pubmed-author:MuellerJJ,
pubmed-author:MullerU JUJ,
pubmed-author:PoeweWW,
pubmed-author:SharmaMM,
pubmed-author:WichmannH EHE
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pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1857-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17130424-Adult,
pubmed-meshheading:17130424-Age Factors,
pubmed-meshheading:17130424-Austria,
pubmed-meshheading:17130424-Brain Chemistry,
pubmed-meshheading:17130424-DNA Mutational Analysis,
pubmed-meshheading:17130424-Dystonic Disorders,
pubmed-meshheading:17130424-Female,
pubmed-meshheading:17130424-Gene Frequency,
pubmed-meshheading:17130424-Genetic Markers,
pubmed-meshheading:17130424-Genetic Predisposition to Disease,
pubmed-meshheading:17130424-Genetic Testing,
pubmed-meshheading:17130424-Genotype,
pubmed-meshheading:17130424-Germany,
pubmed-meshheading:17130424-Haplotypes,
pubmed-meshheading:17130424-Humans,
pubmed-meshheading:17130424-Male,
pubmed-meshheading:17130424-Molecular Chaperones,
pubmed-meshheading:17130424-Mutation,
pubmed-meshheading:17130424-Polymorphism, Single Nucleotide,
pubmed-meshheading:17130424-Sex Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia.
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pubmed:affiliation |
Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, University of Tuebingen, Hoppe-Seyler-Str. 3, 72086 Tuebingen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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