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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-12-25
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pubmed:abstractText |
Members of the classical transient receptor potential protein (TRPC) family are considered as key components of phospholipase C (PLC)-dependent Ca2+ signaling. Previous results obtained in the HEK 293 expression system suggested a physical and functional coupling of TRPC3 to the cardiac-type Na+/Ca2+ exchanger, NCX1 (sodium calcium exchanger 1). This study was designed to test for expression of TRPC3 (transient receptor potential channel 3) and for the existence of a native TRPC3/NCX1 signaling complex in rat cardiac myocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
111-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17129578-Animals,
pubmed-meshheading:17129578-Calcium,
pubmed-meshheading:17129578-Cell Line,
pubmed-meshheading:17129578-Cell Membrane,
pubmed-meshheading:17129578-Cells, Cultured,
pubmed-meshheading:17129578-Homeostasis,
pubmed-meshheading:17129578-Humans,
pubmed-meshheading:17129578-Immunohistochemistry,
pubmed-meshheading:17129578-Immunoprecipitation,
pubmed-meshheading:17129578-Microscopy, Confocal,
pubmed-meshheading:17129578-Myocytes, Cardiac,
pubmed-meshheading:17129578-Rats,
pubmed-meshheading:17129578-Rats, Sprague-Dawley,
pubmed-meshheading:17129578-Signal Transduction,
pubmed-meshheading:17129578-Sodium-Calcium Exchanger,
pubmed-meshheading:17129578-TRPC Cation Channels,
pubmed-meshheading:17129578-Transfection,
pubmed-meshheading:17129578-Type C Phospholipases
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pubmed:year |
2007
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pubmed:articleTitle |
Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex.
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pubmed:affiliation |
Institute of Pharmaceutical Sciences, Pharmacology and Toxicology, Karl-Franzens-University, Graz, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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