Linked Life Data

1712817

Source:http://linkedlifedata.com/resource/pubmed/id/1712817

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:1712817rdf:typepubmed:Citationlld:pubmed
pubmed-article:1712817lifeskim:mentionsumls-concept:C0008151lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C0039194lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C0025252lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C1167331lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C0003241lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C0030956lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C1521761lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C0033268lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C0205164lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C1552861lld:lifeskim
pubmed-article:1712817lifeskim:mentionsumls-concept:C0205171lld:lifeskim
pubmed-article:1712817pubmed:issue2lld:pubmed
pubmed-article:1712817pubmed:dateCreated1991-8-20lld:pubmed
pubmed-article:1712817pubmed:abstractTextThe protective immune response to infection with Chlamydia trachomatis is associated with antibody reactivity to serovar-specific determinants on the major outer membrane protein (MOMP). Because this immunity is T cell dependent, it is essential to define those Th cell determinants that promote natural boosting of the protective antibody response. The gene for MOMP of serovar B was separated into nine overlapping fragments that represent the five C and four V regions. These fragments were expressed as fusion peptides with GST and used to identify the regions of the MOMP that contain T cell determinants recognized in BALB/c mice. We identified peptides that elicit a T cell response to Chlamydia by immunizing mice with the fusion peptides and testing the proliferative response of T cells in vitro to intact organism. For analysis of determinants seen after infection, animals were inoculated with live organism and the T cell proliferative response to each fusion peptide was measured in vitro. In contrast to proliferative analysis in which several regions of the MOMP elicited T cell responses, functional analysis demonstrated that a single fusion peptide, containing V segment three, elicited T cell help in vivo for the production of high titered antisera, specific for protective determinants on the MOMP.lld:pubmed
pubmed-article:1712817pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1712817pubmed:languageenglld:pubmed
pubmed-article:1712817pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1712817pubmed:citationSubsetAIMlld:pubmed
pubmed-article:1712817pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1712817pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1712817pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1712817pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1712817pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1712817pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1712817pubmed:statusMEDLINElld:pubmed
pubmed-article:1712817pubmed:monthJullld:pubmed
pubmed-article:1712817pubmed:issn0022-1767lld:pubmed
pubmed-article:1712817pubmed:authorpubmed-author:StephensR SRSlld:pubmed
pubmed-article:1712817pubmed:authorpubmed-author:AllenJ EJElld:pubmed
pubmed-article:1712817pubmed:authorpubmed-author:LocksleyR MRMlld:pubmed
pubmed-article:1712817pubmed:issnTypePrintlld:pubmed
pubmed-article:1712817pubmed:day15lld:pubmed
pubmed-article:1712817pubmed:volume147lld:pubmed
pubmed-article:1712817pubmed:ownerNLMlld:pubmed
pubmed-article:1712817pubmed:authorsCompleteYlld:pubmed
pubmed-article:1712817pubmed:pagination674-9lld:pubmed
pubmed-article:1712817pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:meshHeadingpubmed-meshheading:1712817-...lld:pubmed
pubmed-article:1712817pubmed:year1991lld:pubmed
pubmed-article:1712817pubmed:articleTitleA single peptide from the major outer membrane protein of Chlamydia trachomatis elicits T cell help for the production of antibodies to protective determinants.lld:pubmed
pubmed-article:1712817pubmed:affiliationDepartment of Biomedical and Environmental Health Sciences, University of California, Berkeley 94720.lld:pubmed
pubmed-article:1712817pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1712817pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:1712817pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1712817lld:pubmed