Linked Life Data

1712765

Source:http://linkedlifedata.com/resource/pubmed/id/1712765

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1991-8-22
pubmed:abstractText
Hypothyroxinemia and hypertriiodothyroninemia may occur in the course of antithyroid drug or 131I treatment for hyperthyroid Graves' disease and toxic multinodular goiter. To determine the frequency of this discordance, we reviewed 62 patients with hyperthyroidism. Among 41 Graves' disease patients treated with antithyroid drugs and/or 131I, discordant serum triiodothyronine (T3) and thyroxine (T4) levels occurred in 26.8%. Of these patients 72.8% had a high serum T3 level associated with a normal serum T4 level, whereas in 27.2% a high serum T3 level was associated with a low serum T4 level. Among 21 toxic multinodular goiter patients, 14.3% had discordant T3 and T4 levels. We conclude that discordance of serum T4 and T3 concentrations is frequently encountered in patients with hyperthyroid Graves' disease and less frequently in toxic multinodular goiter during or after therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0021-2180
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
361-4
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Discordant hypothyroxinemia and hypertriiodothyroninemia in treated patients with hyperthyroid Graves' disease and toxic multinodular goiter.
pubmed:affiliation
Division of Endocrinology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
pubmed:publicationType
Journal Article