Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-11-27
pubmed:abstractText
T cells are critical to control acute infection of a host with retroviruses but they are usually unable to prevent the development of chronic infections. This review summarizes studies from the Friend virus mouse model that reveal some of the mechanisms by which T cells control chronic retroviral infection, and also reveal why these responses ultimately fail to fully eradicate infection. Also summarized are findings from vaccine studies demonstrating the immunological requirements for the prevention of chronic retroviral infection. The implications of these findings for chronic infections in humans are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1093-4715
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1544-51
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Immune control and prevention of chronic Friend retrovirus infection.
pubmed:affiliation
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
pubmed:publicationType
Journal Article, Review