Linked Life Data

17127250

Source:http://linkedlifedata.com/resource/pubmed/id/17127250

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-11-27
pubmed:abstractText
Preeclampsia is a disorder that uniquely affects pregnancy and profoundly alters the short- and long-term health of the mother and fetus. The pathophysiologic processes that underlie preeclampsia can be thought of in two stages: stage 1, reduced placental perfusion, and stage 2, the maternal clinical syndrome. Multiple pathophysiologic processes influence stage one, affecting trophoblast invasion and placental function. These processes in some women result in stage two, with subsequent maternal inflammatory, metabolic, and thrombotic responses, converging to alter vascular and endothelial health. An increasingly comprehensive understanding of these factors is emerging, which we will introduce in this chapter and which will be detailed in the chapters that follow. The translation of this understanding into clinical trials and ultimately into effective preventive and therapeutic measures remains the ultimate goal of preeclampsia research.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1093-4715
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2403-11
pubmed:dateRevised
2007-12-3
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Emerging concepts in preeclampsia investigation.
pubmed:affiliation
Magee-Womens Research Institute and Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural