|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0009429,
umls-concept:C0030705,
umls-concept:C0035525,
umls-concept:C0065055,
umls-concept:C0201950,
umls-concept:C0205147,
umls-concept:C0428466,
umls-concept:C0444669,
umls-concept:C0525038,
umls-concept:C0556895,
umls-concept:C0683956,
umls-concept:C0871261,
umls-concept:C0982327,
umls-concept:C1148363,
umls-concept:C1533728,
umls-concept:C1556094,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2007-2-5
|
|
pubmed:abstractText |
We showed previously that amino acid (aa) substitutions in the HCV core region (HCV-CR) are predictors of non-virological response (NVR) to peginterferon (PEG-IFN) plus ribavirin (RBV) therapy. Here, we determined the predictive factors of sustained virological response (SVR) and early virologic response (EVR) to this treatment.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0168-8278
|
|
pubmed:author |
pubmed-author:AkutaNorioN,
pubmed-author:AraseYasujiY,
pubmed-author:HosakaTetsuyaT,
pubmed-author:IkedaKenjiK,
pubmed-author:KawamuraYusukeY,
pubmed-author:KobayashiMarikoM,
pubmed-author:KobayashiMasahiroM,
pubmed-author:KumadaHiromitsuH,
pubmed-author:SezakiHitomiH,
pubmed-author:SuzukiFumitakaF,
pubmed-author:SuzukiYoshiyukiY,
pubmed-author:YatsujiHiromiH
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
46
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
403-10
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:17126448-Adult,
pubmed-meshheading:17126448-Aged,
pubmed-meshheading:17126448-Amino Acid Substitution,
pubmed-meshheading:17126448-Antiviral Agents,
pubmed-meshheading:17126448-Cholesterol, LDL,
pubmed-meshheading:17126448-Drug Therapy, Combination,
pubmed-meshheading:17126448-Female,
pubmed-meshheading:17126448-Genotype,
pubmed-meshheading:17126448-Hepacivirus,
pubmed-meshheading:17126448-Hepatitis C,
pubmed-meshheading:17126448-Humans,
pubmed-meshheading:17126448-Interferon-alpha,
pubmed-meshheading:17126448-Japan,
pubmed-meshheading:17126448-Male,
pubmed-meshheading:17126448-Middle Aged,
pubmed-meshheading:17126448-Multivariate Analysis,
pubmed-meshheading:17126448-Polyethylene Glycols,
pubmed-meshheading:17126448-Predictive Value of Tests,
pubmed-meshheading:17126448-Recombinant Proteins,
pubmed-meshheading:17126448-Ribavirin,
pubmed-meshheading:17126448-Sensitivity and Specificity,
pubmed-meshheading:17126448-Treatment Outcome,
pubmed-meshheading:17126448-Viral Core Proteins
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Predictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: amino acid substitutions in the core region and low-density lipoprotein cholesterol levels.
|
|
pubmed:affiliation |
Department of Hepatology, Toranomon Hospital, Tokyo, Japan. akuta-gi@umin.ac.jp
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
