| pubmed-article:1712624 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0034802 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0007138 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0005682 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0069515 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0079419 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C1704824 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:1712624 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:1712624 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:1712624 | pubmed:dateCreated | 1991-8-21 | lld:pubmed |
| pubmed-article:1712624 | pubmed:abstractText | Expression of the p53, the epidermal growth factor receptor (EGFr; c-erbB-1) and c-erbB-2 proteins was studied in 82 patients with primary transitional cell carcinoma of the bladder using an immuno-histochemical method. Strong or moderate staining was found in 18% of tumours for p53 with weaker staining in a further 36% giving a total of 54% of tumours stained for p53. Strong staining was found in 15% of tumours for c-erbB-2 and in 31% for the EGFr. Tumours invading the bladder muscle were significantly more likely to be strongly stained positively for p53 and/or EGFr compared with superficial tumours: only 15% of invasive tumours were stained negatively for both p53 and EGFr. No statistical association was found between p53 and EGFr expression. Weakly positive associations were found between the expression of c-erbB-2 and p53 and between muscle invasive tumours and increased expression of c-erbB-2. Alterations in the expression of p53, c-erbB-1 and c-erbB-2 were found frequently in human transitional cell carcinoma of the urinary bladder and may be of clinical use in defining patient sub-groups of differing prognosis. | lld:pubmed |
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| pubmed-article:1712624 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1712624 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1712624 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1712624 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1712624 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:1712624 | pubmed:issn | 0007-0920 | lld:pubmed |
| pubmed-article:1712624 | pubmed:author | pubmed-author:HorneC HCH | lld:pubmed |
| pubmed-article:1712624 | pubmed:author | pubmed-author:WrightCC | lld:pubmed |
| pubmed-article:1712624 | pubmed:author | pubmed-author:LangD RDR | lld:pubmed |
| pubmed-article:1712624 | pubmed:author | pubmed-author:HarrisA LAL | lld:pubmed |
| pubmed-article:1712624 | pubmed:author | pubmed-author:JohnstonPP | lld:pubmed |
| pubmed-article:1712624 | pubmed:author | pubmed-author:NealD EDE | lld:pubmed |
| pubmed-article:1712624 | pubmed:author | pubmed-author:MellorGG | lld:pubmed |
| pubmed-article:1712624 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1712624 | pubmed:volume | 63 | lld:pubmed |
| pubmed-article:1712624 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1712624 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1712624 | pubmed:pagination | 967-70 | lld:pubmed |
| pubmed-article:1712624 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:1712624 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1712624 | pubmed:articleTitle | Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the human urinary bladder. | lld:pubmed |
| pubmed-article:1712624 | pubmed:affiliation | University Department of Pathology, Newcastle-upon-Tyne, UK. | lld:pubmed |
| pubmed-article:1712624 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1712624 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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