|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0008370,
umls-concept:C0017262,
umls-concept:C0023884,
umls-concept:C0037083,
umls-concept:C0185117,
umls-concept:C0205217,
umls-concept:C0332281,
umls-concept:C0596570,
umls-concept:C0678226,
umls-concept:C0919432,
umls-concept:C1334470,
umls-concept:C1710082,
umls-concept:C2911684
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2006-11-27
|
|
pubmed:abstractText |
Profibrogenic TGF-beta signaling in hepatic stellate cells is modulated during transdifferentiation. Strategies to abrogate TGF-beta effects provide promising antifibrotic results, however, in vivo data regarding Smad activation during fibrogenesis are scarce.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1582-1838
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
10
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
922-32
|
|
pubmed:meshHeading |
pubmed-meshheading:17125595-Animals,
pubmed-meshheading:17125595-Bile Ducts,
pubmed-meshheading:17125595-Cholestasis,
pubmed-meshheading:17125595-Immunohistochemistry,
pubmed-meshheading:17125595-Ligation,
pubmed-meshheading:17125595-Liver,
pubmed-meshheading:17125595-Liver Cirrhosis,
pubmed-meshheading:17125595-Male,
pubmed-meshheading:17125595-Rats,
pubmed-meshheading:17125595-Rats, Sprague-Dawley,
pubmed-meshheading:17125595-Signal Transduction,
pubmed-meshheading:17125595-Smad3 Protein,
pubmed-meshheading:17125595-Smad4 Protein,
pubmed-meshheading:17125595-Smad7 Protein,
pubmed-meshheading:17125595-Transforming Growth Factor beta
|
|
pubmed:articleTitle |
Liver fibrogenesis due to cholestasis is associated with increased Smad7 expression and Smad3 signaling.
|
|
pubmed:affiliation |
Department of Plastic and Hand Surgery, University Medical Center Erlangen, Germany.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
