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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-8-9
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pubmed:abstractText |
Fifty-seven magnetic resonance (MR) imaging examinations were obtained at 0.5 T in 19 patients before and after percutaneous ethanol injection (PEI) for 23 hepatocellular carcinoma (HCC) lesions less than 3.5 cm in diameter. Seventeen patients also underwent MR imaging 6 months after completion of therapy. In 11 patients, computed tomography was performed before and after treatment. After PEI, fine-needle biopsy specimens were obtained in all cases. Before treatment, HCC lesions had low signal intensity on T1-weighted images in 13 cases, had the same signal intensity as normal liver parenchyma in six, and had high signal intensity in four; all 23 tumors had high signal intensity on T2-weighted images. After treatment and at 6-month follow-up, all 21 lesions that contained no malignant cells at fine-needle biopsy had high signal intensity on T1-weighted images and had low signal intensity on T2-weighted images. The remaining two HCC lesions in which tumor necrosis was not achieved with PEI displayed a different MR pattern, since the residual neoplastic tissue showed no change in signal intensity on either T1- or T2-weighted images. The authors conclude that MR imaging may be useful for evaluating the effectiveness of PEI in achieving tumor regression.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0033-8419
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
180
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
333-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1712499-Aged,
pubmed-meshheading:1712499-Carcinoma, Hepatocellular,
pubmed-meshheading:1712499-Ethanol,
pubmed-meshheading:1712499-Female,
pubmed-meshheading:1712499-Humans,
pubmed-meshheading:1712499-Injections, Intralesional,
pubmed-meshheading:1712499-Liver Neoplasms,
pubmed-meshheading:1712499-Magnetic Resonance Imaging,
pubmed-meshheading:1712499-Male,
pubmed-meshheading:1712499-Middle Aged,
pubmed-meshheading:1712499-Prospective Studies,
pubmed-meshheading:1712499-Remission Induction,
pubmed-meshheading:1712499-Tomography, X-Ray Computed,
pubmed-meshheading:1712499-alpha-Fetoproteins
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pubmed:year |
1991
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pubmed:articleTitle |
Small hepatocellular carcinoma treated with percutaneous ethanol injection: MR imaging findings.
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pubmed:affiliation |
Department of Radiology, Scientific Institute San Raffaele, University Hospital, Milan, Italy.
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pubmed:publicationType |
Journal Article
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