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pubmed-article:17124721pubmed:abstractTextType 1 diabetes mellitus (T1DM) is a T-cell-mediated autoimmune disease that leads to the destruction of insulin-producing beta cells. Treatment with DiaPep277, a peptide derived from heat-shock protein 60 (hsp60), has been found to slow the deterioration of beta-cell function after clinical onset of diabetes in NOD mice and human adults. Our aim was to evaluate the efficacy and safety of DiaPep277 treatment in attenuating beta-cell destruction in children with recent-onset T1DM.lld:pubmed
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pubmed-article:17124721pubmed:copyrightInfoCopyright 2007 John Wiley & Sons, Ltd.lld:pubmed
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pubmed-article:17124721pubmed:articleTitleHeat-shock protein peptide DiaPep277 treatment in children with newly diagnosed type 1 diabetes: a randomised, double-blind phase II study.lld:pubmed
pubmed-article:17124721pubmed:affiliationThe institute for Endocrinology and Diabetes, National Center of Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.lld:pubmed
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