rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
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pubmed:dateCreated |
2007-5-8
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pubmed:abstractText |
Treatment with DiaPep277, a peptide derived from HSP60, has been shown to preserve beta-cell function in non-obese diabetic mouse (NOD) mice and in a trial with newly diagnosed human patients with type 1 diabetes treated over a 10-month period. This article extends the clinical trial observations to a total of 20 months of treatment to determine the safety and the effects of repeated doses of DiaPep277 on endogenous insulin secretion, metabolic control, and exogenous insulin requirements.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1520-7552
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2007 John Wiley & Sons, Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
292-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17124720-Adolescent,
pubmed-meshheading:17124720-Adult,
pubmed-meshheading:17124720-C-Peptide,
pubmed-meshheading:17124720-Chaperonin 60,
pubmed-meshheading:17124720-Diabetes Mellitus, Type 1,
pubmed-meshheading:17124720-Double-Blind Method,
pubmed-meshheading:17124720-Drug Administration Schedule,
pubmed-meshheading:17124720-Drug Therapy, Combination,
pubmed-meshheading:17124720-Hemoglobin A, Glycosylated,
pubmed-meshheading:17124720-Humans,
pubmed-meshheading:17124720-Hypoglycemic Agents,
pubmed-meshheading:17124720-Insulin,
pubmed-meshheading:17124720-Insulin-Secreting Cells,
pubmed-meshheading:17124720-Male,
pubmed-meshheading:17124720-Middle Aged,
pubmed-meshheading:17124720-Peptide Fragments,
pubmed-meshheading:17124720-Peptides
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pubmed:year |
2007
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pubmed:articleTitle |
Treatment of new-onset type 1 diabetes with peptide DiaPep277 is safe and associated with preserved beta-cell function: extension of a randomized, double-blind, phase II trial.
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pubmed:affiliation |
Department of Internal Medicine, Hadassah-Hebrew University Medical School, Jerusalem, Israel.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Clinical Trial, Phase II
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