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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-12-22
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pubmed:abstractText |
Paroxetine is believed to be a substrate of CYP2D6. However, no information was available indicating drug interaction between paroxetine and inhibitors of CYP2D6. The aim of this study was to examine the effects of terbinafine, a potent inhibitor of CYP2D6, on pharmacokinetics of paroxetine.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0031-6970
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
51-6
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pubmed:meshHeading |
pubmed-meshheading:17124578-Administration, Oral,
pubmed-meshheading:17124578-Adult,
pubmed-meshheading:17124578-Antidepressive Agents, Second-Generation,
pubmed-meshheading:17124578-Antifungal Agents,
pubmed-meshheading:17124578-Area Under Curve,
pubmed-meshheading:17124578-Biological Availability,
pubmed-meshheading:17124578-Chromatography, High Pressure Liquid,
pubmed-meshheading:17124578-Cross-Over Studies,
pubmed-meshheading:17124578-Cytochrome P-450 CYP2D6,
pubmed-meshheading:17124578-Drug Synergism,
pubmed-meshheading:17124578-Female,
pubmed-meshheading:17124578-Humans,
pubmed-meshheading:17124578-Male,
pubmed-meshheading:17124578-Naphthalenes,
pubmed-meshheading:17124578-Paroxetine,
pubmed-meshheading:17124578-Serotonin Uptake Inhibitors
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pubmed:year |
2007
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pubmed:articleTitle |
Terbinafine increases the plasma concentration of paroxetine after a single oral administration of paroxetine in healthy subjects.
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pubmed:affiliation |
Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki 036-8562, Japan. yasufuru@cc.hirosaki-u.ac.jp
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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