Linked Life Data

17124059

Source:http://linkedlifedata.com/resource/pubmed/id/17124059

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-11-24
pubmed:abstractText
Treatment of acute myeloid leukemia (AML) in older adults remains a tremendous challenge. Standard approaches to treatment have resulted in progression-free survival in only a small minority of patients with AML over the age of 60. Elucidation of the molecular genetic events that contribute to the pathogenesis of AML in older patients are providing insights into mechanisms of resistance. This knowledge is also providing new opportunities to begin to refine and direct novel therapies for these heterogeneous diseases. In this case-based review, prognostic factors for treatment outcome in older adults will be covered along with discussion of a risk-based approach to potential therapeutic options, ranging from palliative care to novel therapies and reduced-intensity allogenic transplant.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1520-4391
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-91
pubmed:dateRevised
2008-2-12
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Controversies in treatment of AML: case-based discussion.
pubmed:affiliation
University of Chicago, Section Hem./Onc., 5841 S Maryland, M/C 2115, Chicago IL 60637, USA. wstock@medicine.bsd.uchicago.edu
pubmed:publicationType
Journal Article, Review, Case Reports