rdf:type |
|
lifeskim:mentions |
umls-concept:C0005516,
umls-concept:C0010132,
umls-concept:C0011777,
umls-concept:C0022885,
umls-concept:C0035647,
umls-concept:C0039593,
umls-concept:C0087111,
umls-concept:C0205195,
umls-concept:C0681842,
umls-concept:C0871261,
umls-concept:C1269683,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
1
|
pubmed:dateCreated |
2007-6-18
|
pubmed:abstractText |
Exaggerated corticotropin (ACTH) and cortisol response to the combined dexamethasone (DEX)/corticotropin releasing hormone (CRH) test, indicating impaired regulation of the hypothalamus-pituitary-adrenocortical (HPA) system, is frequently observed in depression. In the present study, we examined whether change in HPA system function during the first weeks of hospitalization predicts response to antidepressant treatment in major depression and thus constitutes a potential biomarker.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0006-3223
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
62
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
47-54
|
pubmed:meshHeading |
pubmed-meshheading:17123470-Adrenocorticotropic Hormone,
pubmed-meshheading:17123470-Antidepressive Agents,
pubmed-meshheading:17123470-Biological Markers,
pubmed-meshheading:17123470-Corticotropin-Releasing Hormone,
pubmed-meshheading:17123470-Depressive Disorder, Major,
pubmed-meshheading:17123470-Dexamethasone,
pubmed-meshheading:17123470-Female,
pubmed-meshheading:17123470-Hospitalization,
pubmed-meshheading:17123470-Humans,
pubmed-meshheading:17123470-Hydrocortisone,
pubmed-meshheading:17123470-Longitudinal Studies,
pubmed-meshheading:17123470-Male,
pubmed-meshheading:17123470-Middle Aged,
pubmed-meshheading:17123470-Prognosis,
pubmed-meshheading:17123470-Treatment Outcome
|
pubmed:year |
2007
|
pubmed:articleTitle |
Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker?
|
pubmed:affiliation |
Max Planck Institute of Psychiatry, Munich, Germany. ising@mpipsykl.mpg.de
|
pubmed:publicationType |
Journal Article,
Comparative Study
|