Linked Life Data

17121605

Source:http://linkedlifedata.com/resource/pubmed/id/17121605

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2006-11-23
pubmed:abstractText
Here we report for the first time the discovery of sheep that have black bones and black muscles. The spectral pattern of pigment extracted from tissues of these black-boned sheep is similar to that of black-boned Chinese silky fowl. Additionally, black-boned sheep have significantly higher plasma colour, tyrosinase activity and kidney function than normal sheep. Synonymous nucleotide substitutions in the tyrosinase (TYR) and melanocortin 1 receptor (MC1R) genes were detected in black-boned sheep when compared with the corresponding sequences in normal sheep. In addition, a missense mutation (215T>C) in exon 2 of tyrosinase-related protein 1 (TYRP1) was detected in black-boned sheep, and this resulted in a putative valine-to-alanine substitution at codon 68 (Val68Ala).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0268-9146
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
586-8
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Physiological and genetic characteristics of black-boned sheep (Ovis aries).
pubmed:affiliation
Yunnan Provincial Laboratory of Animal Nutrition and Feed Science, Kunming 650201, China. dwdxdm@yahoo.com.cn
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't