Linked Life Data

1712077

Source:http://linkedlifedata.com/resource/pubmed/id/1712077

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6329
pubmed:dateCreated
1991-8-5
pubmed:databankReference
pubmed:abstractText
Nitric oxide is a messenger molecule, mediating the effect of endothelium-derived relaxing factor in blood vessels and the cytotoxic actions of macrophages, and playing a part in neuronal communication in the brain. Cloning of a complementary DNA for brain nitric oxide synthase reveals recognition sites for NADPH, FAD, flavin mononucleotide and calmodulin as well as phosphorylation sites, indicating that the synthase is regulated by many different factors. The only known mammalian enzyme with close homology is cytochrome P-450 reductase.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
351
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
714-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:1712077-Amino Acid Oxidoreductases, pubmed-meshheading:1712077-Amino Acid Sequence, pubmed-meshheading:1712077-Animals, pubmed-meshheading:1712077-Base Sequence, pubmed-meshheading:1712077-Binding Sites, pubmed-meshheading:1712077-Calmodulin, pubmed-meshheading:1712077-Cell Line, pubmed-meshheading:1712077-Cerebellum, pubmed-meshheading:1712077-Cloning, Molecular, pubmed-meshheading:1712077-DNA, pubmed-meshheading:1712077-Flavin Mononucleotide, pubmed-meshheading:1712077-Flavin-Adenine Dinucleotide, pubmed-meshheading:1712077-Gene Expression, pubmed-meshheading:1712077-Humans, pubmed-meshheading:1712077-Molecular Sequence Data, pubmed-meshheading:1712077-NADP, pubmed-meshheading:1712077-NADPH-Ferrihemoprotein Reductase, pubmed-meshheading:1712077-Nitric Oxide Synthase, pubmed-meshheading:1712077-Phosphorylation, pubmed-meshheading:1712077-RNA, Messenger, pubmed-meshheading:1712077-Rats, pubmed-meshheading:1712077-Sequence Homology, Nucleic Acid, pubmed-meshheading:1712077-Tissue Distribution, pubmed-meshheading:1712077-Transfection
pubmed:year
1991
pubmed:articleTitle
Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase.
pubmed:affiliation
Department of Neuroscience, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't