Source:http://linkedlifedata.com/resource/pubmed/id/17119156
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2006-11-22
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pubmed:abstractText |
Lipid rafts are liquid-ordered (l(o)) phase microdomains proposed to exist in biological membranes. Rafts have been widely studied by isolating l(o)-phase detergent-resistant membranes (DRMs) from cells. Recent findings have shown that DRMs are not the same as preexisting rafts, prompting a major revision of the raft model. Nevertheless, raft-targeting signals identified by DRM analysis are often required for protein function, implicating rafts in a variety of cell processes.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1548-9213
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
430-9
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pubmed:dateRevised |
2010-1-14
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pubmed:meshHeading |
pubmed-meshheading:17119156-Animals,
pubmed-meshheading:17119156-Cell Membrane,
pubmed-meshheading:17119156-Detergents,
pubmed-meshheading:17119156-Humans,
pubmed-meshheading:17119156-Membrane Microdomains,
pubmed-meshheading:17119156-Membrane Proteins,
pubmed-meshheading:17119156-Signal Transduction
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pubmed:year |
2006
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pubmed:articleTitle |
Lipid rafts, detergent-resistant membranes, and raft targeting signals.
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pubmed:affiliation |
Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA. deborah.brown@sunysb.edu
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pubmed:publicationType |
Journal Article,
Review,
Research Support, N.I.H., Extramural
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