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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-20
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pubmed:abstractText |
We describe a successful outcome of long-term interferon beta-1b therapy in a patient who had multiple sclerosis (MS) with positive serum autoantibody to muscle acetylcholine receptor (AChR-Ab). Because of the reported possible causative linkage between interferon beta-1b and myasthenia gravis (MG), the presence of the pathogenic antibody complicated therapeutic strategies. We carefully observed the patient for further 6 months before the treatment, excluding symptomatic MG. The interferon beta-1b therapy then provided a clinical benefit. Hopefully this report will allow MS patients in similar situations to make more rapid, unprejudiced judgments than our patients.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
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pubmed:issn |
0303-8467
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
277-8
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pubmed:dateRevised |
2009-10-14
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pubmed:meshHeading |
pubmed-meshheading:17118531-Adjuvants, Immunologic,
pubmed-meshheading:17118531-Adult,
pubmed-meshheading:17118531-Antibodies, Anti-Idiotypic,
pubmed-meshheading:17118531-Autoantibodies,
pubmed-meshheading:17118531-Female,
pubmed-meshheading:17118531-Humans,
pubmed-meshheading:17118531-Interferon-beta,
pubmed-meshheading:17118531-Multiple Sclerosis,
pubmed-meshheading:17118531-Muscle, Skeletal,
pubmed-meshheading:17118531-Myasthenia Gravis,
pubmed-meshheading:17118531-Receptors, Cholinergic
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pubmed:year |
2007
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|
pubmed:articleTitle |
Interferon causes no myasthenia in a seropositive patient with multiple sclerosis.
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pubmed:affiliation |
Department of Neurology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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