rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2006-12-5
|
pubmed:abstractText |
APOE polymorphism has received extensive attention as a risk factor for Parkinson's disease (PD), but findings have been equivocal. Analysis of APOE variants in an Australian PD case-control sample revealed a robust association between genotype and age-at-onset (AAO) of PD in women (P=0.0008). These data not only further implicate APOE in PD, but also provide a stark example of the effects that gender may play in complex disorders.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0304-3940
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
411
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
185-8
|
pubmed:meshHeading |
pubmed-meshheading:17113231-Age of Onset,
pubmed-meshheading:17113231-Aged,
pubmed-meshheading:17113231-Analysis of Variance,
pubmed-meshheading:17113231-Apolipoproteins E,
pubmed-meshheading:17113231-Case-Control Studies,
pubmed-meshheading:17113231-Chi-Square Distribution,
pubmed-meshheading:17113231-Female,
pubmed-meshheading:17113231-Genetic Predisposition to Disease,
pubmed-meshheading:17113231-Humans,
pubmed-meshheading:17113231-Male,
pubmed-meshheading:17113231-Middle Aged,
pubmed-meshheading:17113231-Parkinson Disease,
pubmed-meshheading:17113231-Polymorphism, Genetic,
pubmed-meshheading:17113231-Sex Characteristics
|
pubmed:year |
2007
|
pubmed:articleTitle |
Association of APOE with Parkinson disease age-at-onset in women.
|
pubmed:affiliation |
University of Queensland, School of Medicine, Department of Neurology, Princess Alexandra Hospital, Brisbane, Australia.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|