Linked Life Data

17110292

Source:http://linkedlifedata.com/resource/pubmed/id/17110292

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-11-19
pubmed:abstractText
Ultrafine, or nano-, particles (< 100 nm) have been associated in epidemiological, human clinical, and animal studies with adverse cardiopulmonary outcomes. Deposition of inhaled ultrafine particles in the respiratory tract is mainly governed by diffusion and is most efficient for alveolar regions of the lung, although deposition occurs in other regions, too. The nose is also a very efficient filter for smaller ultrafine (< 5 nm, diffusion) particles. Solid poorly-soluble ultrafine particles are not efficiently cleared via mucociliary or macrophage-mediated mechanisms and are, thus, likely to be taken up by epithelial cells and translocate to extrapulmonary sites (interstitium, lymph and blood circulation, neurons). These translocation processes are explored here as well potential consequences that result from exposure of extrapulmonary organs to inhaled ultrafine particles.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1526-0046
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
785-96
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Translocation and effects of ultrafine particles outside of the lung.
pubmed:affiliation
Department of Environmental Medicine, University of Rochester, Rochester, NY 14642, USA. alison_elder@urmc.rochester.edu
pubmed:publicationType
Journal Article, Review