Source:http://linkedlifedata.com/resource/pubmed/id/17109095
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2006-11-19
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| pubmed:abstractText |
This report focuses on changes in the nasopharyngeal bacterial flora before and after administration of antimicrobial agents in 172 cases of acute upper respiratory infection in patients aged 6 years or younger. The antimicrobial agents administered were amoxicillin (AMPC) (34%), clavulanic acid/amoxicillin compound (11%), cefditren pivoxil (CDTR-PI) (43%), and others (12%). Changes in nasopharyngeal bacterial flora were investigated with reexaminations conducted after 2-5 days (day 2-5 subgroup), 6-10 days (day 6-10 subgroup), and 11 days and thereafter. There was a significant reduction in the Streptococcus pneumoniae detected in the group administered AMPC (AMPC group) in the day 2-5 subgroup and the day 6-10 subgroup. There was also a significant decrease in H. influenzae in the group administered CDTR-PI (CDTR-PI group) in the day 2-5 subgroup. From this it was inferred that for the most part significant changes in infectious nasopharyngeal bacteria occurred in the day 2-5 subgroups. However, a significant improvement in the degree of inflammation, as indicated by leukocyte infiltration images for the AMPC group, was observed in the day 2-5 subgroup, and for the CDTR-PI group in the day 6-10 subgroup. On the other hand, in both the antimicrobial agent groups, S. pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis were newly detected at reexamination. Furthermore, a difference in the incidence of these bacteria was observed between the 2 antimicrobial agent groups. It was suggested that such phenomena related to the survival of resistant strains or a recurrence otitis media.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Oct
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| pubmed:issn |
1341-321X
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| pubmed:author |
pubmed-author:BabaShunkichiS,
pubmed-author:FurukawaMituruM,
pubmed-author:FuruyaNobuhikoN,
pubmed-author:HaraKoheiK,
pubmed-author:InoueMatsuhisaM,
pubmed-author:KagaKimitakaK,
pubmed-author:KobayashiKunihikoK,
pubmed-author:KobayashiToshimitsuT,
pubmed-author:KohnoShigeruS,
pubmed-author:KoizumiShoichiS,
pubmed-author:KonnoMasatoshiM,
pubmed-author:MatsumotoFumioF,
pubmed-author:MatsushimaToshiharuT,
pubmed-author:MikawaHarukiH,
pubmed-author:MorikawaAkihiroA,
pubmed-author:MoriyamaHiroshiH,
pubmed-author:NishimuraTadaoT,
pubmed-author:OkamotoYoshitakaY,
pubmed-author:SunakawaKeisukeK,
pubmed-author:UbukataKimikoK,
pubmed-author:YamanakaNoboruN,
pubmed-author:YoshizawaYasuyukiY
|
| pubmed:issnType |
Print
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
305-30
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| pubmed:meshHeading |
pubmed-meshheading:17109095-Anti-Infective Agents,
pubmed-meshheading:17109095-Child,
pubmed-meshheading:17109095-Child, Preschool,
pubmed-meshheading:17109095-Drug Resistance,
pubmed-meshheading:17109095-Female,
pubmed-meshheading:17109095-Haemophilus Infections,
pubmed-meshheading:17109095-Haemophilus influenzae,
pubmed-meshheading:17109095-Humans,
pubmed-meshheading:17109095-Infant,
pubmed-meshheading:17109095-Male,
pubmed-meshheading:17109095-Moraxella (Branhamella) catarrhalis,
pubmed-meshheading:17109095-Moraxellaceae Infections,
pubmed-meshheading:17109095-Nasopharynx,
pubmed-meshheading:17109095-Otitis Media,
pubmed-meshheading:17109095-Pneumococcal Infections,
pubmed-meshheading:17109095-Polymerase Chain Reaction,
pubmed-meshheading:17109095-Respiratory Tract Infections,
pubmed-meshheading:17109095-Streptococcus pneumoniae
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| pubmed:year |
2006
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| pubmed:articleTitle |
Study of nasopharyngeal bacterial flora. Second report. Variations in nasopharyngeal bacterial flora in children aged 6 years or younger when administered antimicrobial agents. Part 2.
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| pubmed:affiliation |
Teikyo University School of Medicine, Tokyo, Japan. mrsa@interlink.or.jp
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| pubmed:publicationType |
Journal Article
|