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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-16
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pubmed:abstractText |
Atopic dermatitis (AD) is a chronic multifactorial allergic disease with unclear etiology. The antimicrobial human beta-defensin 1 is chemotactic for dendritic cells, which are important regulators of allergic immune responses. In an attempt to identify useful markers that could predict susceptibility to AD, we investigated single nucleotide polymorphisms (SNPs) of the beta-defensin 1 gene (DEFB1) with potential functional consequences.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1018-2438
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
142
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
211-8
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pubmed:meshHeading |
pubmed-meshheading:17108702-Adolescent,
pubmed-meshheading:17108702-Adult,
pubmed-meshheading:17108702-Age of Onset,
pubmed-meshheading:17108702-Breast Feeding,
pubmed-meshheading:17108702-Child,
pubmed-meshheading:17108702-Child, Preschool,
pubmed-meshheading:17108702-Dermatitis, Atopic,
pubmed-meshheading:17108702-Female,
pubmed-meshheading:17108702-Genetic Predisposition to Disease,
pubmed-meshheading:17108702-Humans,
pubmed-meshheading:17108702-Infant,
pubmed-meshheading:17108702-Linkage Disequilibrium,
pubmed-meshheading:17108702-Male,
pubmed-meshheading:17108702-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:17108702-Polymorphism, Single Nucleotide,
pubmed-meshheading:17108702-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17108702-beta-Defensins
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pubmed:year |
2007
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pubmed:articleTitle |
Association of beta-defensin 1 single nucleotide polymorphisms with atopic dermatitis.
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pubmed:affiliation |
PhD Program in Human Genetics, Universidad de Guadalajara, Guadalajara, Jalisco, México.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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