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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-1-25
pubmed:abstractText
Pre-operative lymphoscintigraphy (LS) is an important part of successful sentinel lymph node (SLN) biopsy in most melanoma treatment centers. The test accurately maps lymphatic drainage from cutaneous melanoma sites and has been shown to be reproducible in prospective studies. Its reproducibility has not been tested, however, in routine clinical practice. Occasionally, after LS has been performed to map the location of SLNs, the patient is unable to proceed to SLN biopsy surgery within the time limit imposed by the radioactive decay of the 99mTc label attached to the colloid particles. In this situation, the surgery is rescheduled and LS repeated to relabel the SLNs so that they may be accurately biopsied. This has happened on 21 occasions at the Sydney Melanoma Unit and we have performed a retrospective analysis of the reproducibility of the LS results. In 19 patients, the same SLNs were shown in the same locations on the two studies. Two patients had discrepant results. One showed two extra interval nodes on the back as well as concordant flow to SLNs in each axilla. The other with a leg melanoma showed the same groin SLNs but failed to relabel the two popliteal SLNs on the second study. SLN locations were identical during 95%, and SLNs were identical 94% of the time. These results indicate that in routine clinical practice LS is a highly reproducible procedure to locate and radiolabel the SLNs prior to biopsy in patients with melanoma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1068-9265
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
899-905
pubmed:dateRevised
2007-7-18
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
The reproducibility in routine clinical practice of sentinel lymph node identification by pre-operative lymphoscintigraphy in patients with cutaneous melanoma.
pubmed:affiliation
Nuclear Medicine and Diagnostic Ultrasound, RPAH Medical Centre and Discipline of Medicine, The University of Sydney, Sydney, NSW, Australia. ruren@mail.usyd.edu.au
pubmed:publicationType
Journal Article