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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-11-14
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pubmed:abstractText |
Normal prothrombin time (PT) and partial thromboplastin time (PTT) are recommended for administration of recombinant tissue-plasminogen activator (rt-PA) in stroke, but waiting for results can delay use. We examined the charts of 365 stroke patients to assess predetermined risk factors associated with elevated PT/PTT. Elevated PT/PTT can be predicted in patients taking warfarin or heparin/heparinoid or on hemodialysis, according to emergency department triage, with 100% sensitivity and 94.7% specificity. These results could be applied to rt-PA candidates and reduce potential delays.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1665-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17101901-Adult,
pubmed-meshheading:17101901-Aged,
pubmed-meshheading:17101901-Aged, 80 and over,
pubmed-meshheading:17101901-Anticoagulants,
pubmed-meshheading:17101901-Antiphospholipid Syndrome,
pubmed-meshheading:17101901-Brain Ischemia,
pubmed-meshheading:17101901-Coagulation Protein Disorders,
pubmed-meshheading:17101901-Female,
pubmed-meshheading:17101901-Heparin,
pubmed-meshheading:17101901-Humans,
pubmed-meshheading:17101901-Kidney Failure, Chronic,
pubmed-meshheading:17101901-Liver Failure,
pubmed-meshheading:17101901-Male,
pubmed-meshheading:17101901-Middle Aged,
pubmed-meshheading:17101901-Partial Thromboplastin Time,
pubmed-meshheading:17101901-Predictive Value of Tests,
pubmed-meshheading:17101901-Prothrombin Time,
pubmed-meshheading:17101901-Recombinant Proteins,
pubmed-meshheading:17101901-Renal Dialysis,
pubmed-meshheading:17101901-Stroke,
pubmed-meshheading:17101901-Time Factors,
pubmed-meshheading:17101901-Tissue Plasminogen Activator,
pubmed-meshheading:17101901-Triage,
pubmed-meshheading:17101901-Warfarin
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pubmed:year |
2006
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pubmed:articleTitle |
Predicting abnormal coagulation in ischemic stroke: reducing delay in rt-PA use.
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pubmed:affiliation |
Cerebrovascular Division, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
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pubmed:publicationType |
Journal Article,
Validation Studies
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