Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2006-11-13
pubmed:abstractText
High-altitude pulmonary edema (HAPE), which develops on exertion under hypoxic conditions, aggravates due to endothelial dysfunction. Repeat events of the disorder suggests of genetic susceptibility. Endothelial nitric oxide synthase gene (NOS3), a regulator of vasodilation, has emerged as a strong candidate marker. In the present study, we investigated G894T, 27-base-pair 4b/4a (variable number of tandem repeat), -922A/G, and -786T/C polymorphisms of NOS3, individually or in combination, for an association with HAPE.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0012-3692
pubmed:author
pubmed:issnType
Print
pubmed:volume
130
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1511-9
pubmed:meshHeading
pubmed-meshheading:17099031-Adult, pubmed-meshheading:17099031-Altitude, pubmed-meshheading:17099031-Anoxia, pubmed-meshheading:17099031-Biological Markers, pubmed-meshheading:17099031-Case-Control Studies, pubmed-meshheading:17099031-Cross-Sectional Studies, pubmed-meshheading:17099031-DNA, pubmed-meshheading:17099031-Gene Frequency, pubmed-meshheading:17099031-Genetic Predisposition to Disease, pubmed-meshheading:17099031-Genotype, pubmed-meshheading:17099031-Haplotypes, pubmed-meshheading:17099031-Heterozygote, pubmed-meshheading:17099031-Humans, pubmed-meshheading:17099031-Male, pubmed-meshheading:17099031-Nitric Oxide Synthase Type III, pubmed-meshheading:17099031-Nitrogen Oxides, pubmed-meshheading:17099031-Polymorphism, Genetic, pubmed-meshheading:17099031-Pulmonary Edema, pubmed-meshheading:17099031-Risk Factors, pubmed-meshheading:17099031-Tandem Repeat Sequences
pubmed:year
2006
pubmed:articleTitle
Heterozygotes of NOS3 polymorphisms contribute to reduced nitrogen oxides in high-altitude pulmonary edema.
pubmed:affiliation
Functional Genomics Unit, Institute of Genomics and Integrative Biology, Mall Rd, Delhi-110 007, India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't