| pubmed-article:1709758 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1709758 | lifeskim:mentions | umls-concept:C0004651 | lld:lifeskim |
| pubmed-article:1709758 | lifeskim:mentions | umls-concept:C0014834 | lld:lifeskim |
| pubmed-article:1709758 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:1709758 | lifeskim:mentions | umls-concept:C0035711 | lld:lifeskim |
| pubmed-article:1709758 | lifeskim:mentions | umls-concept:C0242850 | lld:lifeskim |
| pubmed-article:1709758 | lifeskim:mentions | umls-concept:C1537998 | lld:lifeskim |
| pubmed-article:1709758 | lifeskim:mentions | umls-concept:C1549781 | lld:lifeskim |
| pubmed-article:1709758 | lifeskim:mentions | umls-concept:C1706536 | lld:lifeskim |
| pubmed-article:1709758 | pubmed:issue | 5008 | lld:pubmed |
| pubmed-article:1709758 | pubmed:dateCreated | 1991-6-26 | lld:pubmed |
| pubmed-article:1709758 | pubmed:abstractText | Some strains of Escherichia coli contain retroelements (retrons) that encode genes for reverse transcriptase and branched, multicopy, single-stranded DNA (msDNA) linked to RNA. However, the origin of retrons is unknown. A P4-like cryptic prophage was found that contains a retroelement (retron Ec73) for msDNA-Ec73 in an E. coli clinical strain. The entire genome of this prophage, named phi R73, is 12.7 kilobase pairs and is flanked by 29-base pair direct repeats derived from the 3' end of the selenocystyl transfer RNA gene (selC). P2 bacteriophage caused excision of the phi R73 prophage and acted as a helper to package phi R73 DNA into an infectious virion. The newly formed phi R73 closely resembled P4 as a virion and in its lytic growth. Retronphage phi R73 lysogenized a new host strain, reintegrating its genome into the selC gene of the host chromosome and enabling the newly formed lysogens to produce msDNA-Ec73. Hence, retron Ec73 can be transferred intercellularly as part of the genome of a helper-dependent retronphage. | lld:pubmed |
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| pubmed-article:1709758 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1709758 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1709758 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1709758 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1709758 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1709758 | pubmed:month | May | lld:pubmed |
| pubmed-article:1709758 | pubmed:issn | 0036-8075 | lld:pubmed |
| pubmed-article:1709758 | pubmed:author | pubmed-author:InouyeMM | lld:pubmed |
| pubmed-article:1709758 | pubmed:author | pubmed-author:InouyeSS | lld:pubmed |
| pubmed-article:1709758 | pubmed:author | pubmed-author:SixE WEW | lld:pubmed |
| pubmed-article:1709758 | pubmed:author | pubmed-author:SunshineM GMG | lld:pubmed |
| pubmed-article:1709758 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1709758 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:1709758 | pubmed:volume | 252 | lld:pubmed |
| pubmed-article:1709758 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1709758 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1709758 | pubmed:pagination | 969-71 | lld:pubmed |
| pubmed-article:1709758 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:1709758 | pubmed:meshHeading | pubmed-meshheading:1709758-... | lld:pubmed |
| pubmed-article:1709758 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1709758 | pubmed:articleTitle | Retronphage phi R73: an E. coli phage that contains a retroelement and integrates into a tRNA gene. | lld:pubmed |
| pubmed-article:1709758 | pubmed:affiliation | Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey at Rutgers, Piscataway 08854. | lld:pubmed |
| pubmed-article:1709758 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1709758 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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