rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-2-2
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pubmed:abstractText |
The major antigen implicated in the antiphospholipid syndrome is beta2-glycoprotein I (beta2GPI). Dimerized beta2GPI binds to apolipoprotein E receptor 2' (apoER2') on platelets and increases platelet adhesion to collagen under conditions of flow.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/LDL-Receptor Related Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Multiprotein Complexes,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Glycoprotein GPIb-IX...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Lipoprotein,
http://linkedlifedata.com/resource/pubmed/chemical/beta 2-Glycoprotein I,
http://linkedlifedata.com/resource/pubmed/chemical/glycocalicin,
http://linkedlifedata.com/resource/pubmed/chemical/low density lipoprotein...
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1538-7933
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
369-77
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17096706-Blood Platelets,
pubmed-meshheading:17096706-Collagen,
pubmed-meshheading:17096706-Dimerization,
pubmed-meshheading:17096706-Humans,
pubmed-meshheading:17096706-Immunoassay,
pubmed-meshheading:17096706-LDL-Receptor Related Proteins,
pubmed-meshheading:17096706-Multiprotein Complexes,
pubmed-meshheading:17096706-Perfusion,
pubmed-meshheading:17096706-Platelet Adhesiveness,
pubmed-meshheading:17096706-Platelet Aggregation,
pubmed-meshheading:17096706-Platelet Glycoprotein GPIb-IX Complex,
pubmed-meshheading:17096706-Receptors, Cell Surface,
pubmed-meshheading:17096706-Receptors, Lipoprotein,
pubmed-meshheading:17096706-Stress, Mechanical,
pubmed-meshheading:17096706-Surface Plasmon Resonance,
pubmed-meshheading:17096706-beta 2-Glycoprotein I
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pubmed:year |
2007
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pubmed:articleTitle |
Platelet adhesion to dimeric beta-glycoprotein I under conditions of flow is mediated by at least two receptors: glycoprotein Ibalpha and apolipoprotein E receptor 2'.
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pubmed:affiliation |
Laboratory of Clinical Chemistry and Haematology, University Medical Centre Utrecht, Utrecht, the Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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