17096678

Source:http://linkedlifedata.com/resource/pubmed/id/17096678

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0032659, umls-concept:C0087111, umls-concept:C0201734, umls-concept:C0814030, umls-concept:C1268900, umls-concept:C1709518
pubmed:issue	6
pubmed:dateCreated	2007-5-18
pubmed:abstractText	To develop a population pharmacokinetic/pharmacodynamic (PK/PD) model of the hypothalamic-pituitary-gonadal (HPG) axis describing the changes in luteinizing hormone (LH) and testosterone concentrations following treatment with the gonadotropin-releasing hormone (GnRH) agonist triptorelin and the GnRH receptor blocker degarelix.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-10087026, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-10407987, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-10709155, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-10794807, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-10801222, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-11397836, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-11462984, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-11468938, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-11485933, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-11502441, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-11705778, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-11768292, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-11907162, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-12638392, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-12878745, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-14592699, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-15139513, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-15669774, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-16078134, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-1615214, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-1615215, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-16215845, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-1823867, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-2940625, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-2974680, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-3111341, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-6210706, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-8897868, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-9437552, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-9531874, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-9688887, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-9843750, http://linkedlifedata.com/resource/pubmed/commentcorrection/17096678-9848124
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7503323
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Gonadotropin-Releasing Hormone, http://linkedlifedata.com/resource/pubmed/chemical/Luteinizing Hormone, http://linkedlifedata.com/resource/pubmed/chemical/Oligopeptides, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, LHRH, http://linkedlifedata.com/resource/pubmed/chemical/Testosterone, http://linkedlifedata.com/resource/pubmed/chemical/Triptorelin Pamoate, http://linkedlifedata.com/resource/pubmed/chemical/acetyl-2-naphthylalanyl-3-chlorophen...
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0306-5251
pubmed:author	pubmed-author:AgersøHenrikH, pubmed-author:JonssonE NiclasEN, pubmed-author:KarlssonMats OMO, pubmed-author:MadsenHenrikH, pubmed-author:NielsenHenrik AHA, pubmed-author:SenderovitzThomasT, pubmed-author:TornøeChristoffer WCW
pubmed:issnType	Print
pubmed:volume	63
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	648-64
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:17096678-Dose-Response Relationship, Drug, pubmed-meshheading:17096678-Feedback, Physiological, pubmed-meshheading:17096678-Gonadotropin-Releasing Hormone, pubmed-meshheading:17096678-Humans, pubmed-meshheading:17096678-Luteinizing Hormone, pubmed-meshheading:17096678-Male, pubmed-meshheading:17096678-Models, Biological, pubmed-meshheading:17096678-Oligopeptides, pubmed-meshheading:17096678-Pituitary Gland, pubmed-meshheading:17096678-Receptors, LHRH, pubmed-meshheading:17096678-Testosterone, pubmed-meshheading:17096678-Triptorelin Pamoate
pubmed:year	2007
pubmed:articleTitle	Population pharmacokinetic/pharmacodynamic (PK/PD) modelling of the hypothalamic-pituitary-gonadal axis following treatment with GnRH analogues.
pubmed:affiliation	Experimental Medicine, Ferring Pharmaceuticals A/S, Copenhagen, Denmark. christoffer.tornoe@fda.hhs.gov
pubmed:publicationType	Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study