Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2006-11-10
pubmed:abstractText
The BOLITA (BOL) gene, an AP2/ERF transcription factor, was characterized with the help of an activation tag mutant and overexpression lines in Arabidopsis and tobacco. The leaf size of plants overexpressing BOL was smaller than wild type plants due to a reduction in both cell size and cell number. Moreover, severe overexpressors showed ectopic callus formation in roots. Accordingly, global gene expression analysis using the overexpression mutant reflected the alterations in cell proliferation, differentiation and growth through expression changes in RBR, CYCD, and TCP genes, as well as genes involved in cell expansion (i.e. expansins and the actin remodeling factor ADF5). Furthermore, the expression of hormone signaling (i.e. auxin and cytokinin), biosynthesis (i.e. ethylene and jasmonic acid) and regulatory genes was found to be perturbed in bol-D mutant leaves.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0167-4412
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
825-43
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:17096212-Arabidopsis, pubmed-meshheading:17096212-Arabidopsis Proteins, pubmed-meshheading:17096212-Cell Differentiation, pubmed-meshheading:17096212-Cell Division, pubmed-meshheading:17096212-Cell Size, pubmed-meshheading:17096212-Culture Techniques, pubmed-meshheading:17096212-Cyclins, pubmed-meshheading:17096212-Gene Expression Regulation, Developmental, pubmed-meshheading:17096212-Gene Expression Regulation, Plant, pubmed-meshheading:17096212-Genome, Plant, pubmed-meshheading:17096212-Glucuronidase, pubmed-meshheading:17096212-Mutagenesis, Insertional, pubmed-meshheading:17096212-Mutation, pubmed-meshheading:17096212-Phenotype, pubmed-meshheading:17096212-Plant Leaves, pubmed-meshheading:17096212-Plants, Genetically Modified, pubmed-meshheading:17096212-Promoter Regions, Genetic, pubmed-meshheading:17096212-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:17096212-Signal Transduction, pubmed-meshheading:17096212-Tobacco, pubmed-meshheading:17096212-Transcription Factors
pubmed:year
2006
pubmed:articleTitle
BOLITA, an Arabidopsis AP2/ERF-like transcription factor that affects cell expansion and proliferation/differentiation pathways.
pubmed:affiliation
Plant Research International, Wageningen University and Research Centre, PO Box 16, 6700 AA, Wageningen, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't