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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5A
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pubmed:dateCreated |
2006-11-10
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pubmed:abstractText |
Aurora-B, a chromosomal passenger protein forming a complex with INCENP (inner centromere protein) and survivin, regulates stable bipolar spindle-kinetochore attachment in mitosis and chromosome segregation and cytokinesis. It was recently documented that Aurora-B directly phosphorylated histone H3, not only at Ser10, but also at Ser28, which contributed to chromosome number instability and mitotic chromosome condensation. This study aimed at investigating the expression of Aurora-B kinase (Aurora-B) and phosphorylated histone H3 (H3-P) and their roles in hepatocellular carcinogenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3585-93
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pubmed:dateRevised |
2011-7-11
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pubmed:meshHeading |
pubmed-meshheading:17094487-Adult,
pubmed-meshheading:17094487-Alternative Splicing,
pubmed-meshheading:17094487-Animals,
pubmed-meshheading:17094487-Base Sequence,
pubmed-meshheading:17094487-Blotting, Western,
pubmed-meshheading:17094487-COS Cells,
pubmed-meshheading:17094487-Carcinoma, Hepatocellular,
pubmed-meshheading:17094487-Cell Differentiation,
pubmed-meshheading:17094487-Cercopithecus aethiops,
pubmed-meshheading:17094487-Female,
pubmed-meshheading:17094487-Histones,
pubmed-meshheading:17094487-Humans,
pubmed-meshheading:17094487-Immunoenzyme Techniques,
pubmed-meshheading:17094487-Liver Neoplasms,
pubmed-meshheading:17094487-Male,
pubmed-meshheading:17094487-Middle Aged,
pubmed-meshheading:17094487-Molecular Sequence Data,
pubmed-meshheading:17094487-Phosphorylation,
pubmed-meshheading:17094487-Protein-Serine-Threonine Kinases,
pubmed-meshheading:17094487-RNA, Messenger,
pubmed-meshheading:17094487-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17094487-Sequence Homology, Nucleic Acid,
pubmed-meshheading:17094487-Transfection,
pubmed-meshheading:17094487-Tumor Cells, Cultured
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pubmed:articleTitle |
Expression of Aurora-B kinase and phosphorylated histone H3 in hepatocellular carcinoma.
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pubmed:affiliation |
Molecular and Pathology, School of Medicine, University of Toyama, Sugitani 2630, Toyama, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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