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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1991-6-4
|
| pubmed:abstractText |
Quantitative immunohistochemistry was used to compare the distributions of keratins and desmoplakins in human gingiva and peri-implant mucosa (three specimens each). In gingiva, keratin 1 (a marker of cornification) and desmoplakins I & II (markers of desmosomes) stained most heavily in granular strata followed by corneal strata; keratin 13, a marker of non-cornifying stratified squamous cells, stained most heavily in suprabasal strata of oral sulcular epithelium. Keratin 19, a marker for junctional epithelium, stained the basal stratum of oral sulcular epithelium most heavily. In peri-implant mucosa, the patterns of staining were similar, except that staining for desmoplakins I & II was generally significantly reduced compared with gingiva, and junctional epithelium co-expressed keratins 13 and 19. Peri-implant junctional epithelial cells attached to titanium implant abutments were removed by trypsin/EDTA digestion, and also exhibited co-expression of keratins 13 and 19. Inflammatory cell infiltration was associated with reduction of keratin 1 staining in gingiva. The data indicate that the epithelia of gingiva and peri-implant mucosa are not composed of identical cell populations.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
D
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0022-0345
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
70
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
899-905
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1708791-Analysis of Variance,
pubmed-meshheading:1708791-Connective Tissue Cells,
pubmed-meshheading:1708791-Cytoskeletal Proteins,
pubmed-meshheading:1708791-Dental Implantation, Endosseous,
pubmed-meshheading:1708791-Dental Implants,
pubmed-meshheading:1708791-Desmoplakins,
pubmed-meshheading:1708791-Desmosomes,
pubmed-meshheading:1708791-Epithelial Cells,
pubmed-meshheading:1708791-Epithelium,
pubmed-meshheading:1708791-Gingiva,
pubmed-meshheading:1708791-Humans,
pubmed-meshheading:1708791-Image Processing, Computer-Assisted,
pubmed-meshheading:1708791-Immunoenzyme Techniques,
pubmed-meshheading:1708791-Immunohistochemistry,
pubmed-meshheading:1708791-Keratins,
pubmed-meshheading:1708791-Lymphocytes,
pubmed-meshheading:1708791-Mouth Mucosa,
pubmed-meshheading:1708791-Staining and Labeling,
pubmed-meshheading:1708791-Video Recording
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Quantitative immunohistochemical analysis of keratins and desmoplakins in human gingiva and peri-implant mucosa.
|
| pubmed:affiliation |
Department of Prosthodontics, Faculty of Dentistry, University of Toronto, Ontario, Canada.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|