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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2006-11-6
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pubmed:abstractText |
Despite aggressive chemotherapy, radiotherapy, surgery, or combination approaches, the survival rate of patients with esophageal cancer remains poor. Recent studies have suggested that constitutive activation of the Hedgehog (Hh) pathway in cancers of the digestive tract may contribute to the growth and maintenance of cancer. However, the relationship between Hh signaling and therapeutic response is unknown.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AjaniJafferJ,
pubmed-author:ApisarnthanaraxSmithS,
pubmed-author:ChaoK S CliffordKS,
pubmed-author:IzzoJulie GJG,
pubmed-author:KomakiRitsukoR,
pubmed-author:LiaoZhongxingZ,
pubmed-author:LuthraRajyalashmiR,
pubmed-author:MalhotraUshaU,
pubmed-author:Sims-MourtadaJenniferJ,
pubmed-author:WuTsung-TehTT,
pubmed-author:van der KogelAlbertA
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6565-72
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17085672-Adenocarcinoma,
pubmed-meshheading:17085672-Animals,
pubmed-meshheading:17085672-Antineoplastic Agents,
pubmed-meshheading:17085672-Blotting, Western,
pubmed-meshheading:17085672-Cell Proliferation,
pubmed-meshheading:17085672-Clinical Trials as Topic,
pubmed-meshheading:17085672-Drug Resistance, Neoplasm,
pubmed-meshheading:17085672-Esophageal Neoplasms,
pubmed-meshheading:17085672-Hedgehog Proteins,
pubmed-meshheading:17085672-Humans,
pubmed-meshheading:17085672-Immunohistochemistry,
pubmed-meshheading:17085672-Mice,
pubmed-meshheading:17085672-Mice, Nude,
pubmed-meshheading:17085672-RNA Interference,
pubmed-meshheading:17085672-Radiation Tolerance,
pubmed-meshheading:17085672-Radiotherapy,
pubmed-meshheading:17085672-Xenograft Model Antitumor Assays
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pubmed:year |
2006
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pubmed:articleTitle |
Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response.
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pubmed:affiliation |
Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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