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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-12-29
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pubmed:abstractText |
Our whole-genome microarray studies of Neisseria meningitidis MC58 previously identified a set of 153 genes whose transcription was activated during growth in iron. In this study, Fur-mediated regulation of the iron-activated nspA gene was confirmed, whereas iron-activated regulation of the secY gene was demonstrated to be Fur independent. Analysis of the Fur binding sequences in the nspA gene and an additional iron-activated and Fur-regulated gene identified a hexameric (G/T)ATAAT unit in the operator regions of these genes similar to that observed in Fur- and iron-repressed genes. These studies indicate that the expression of the iron-activated nspA and secY genes in N. meningitidis occur by Fur-dependent and -independent mechanisms, respectively.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-10338491,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-10456958,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-10850997,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-10922061,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-11000456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-11782507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-11886560,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-11917098,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-12081969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-12379678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-12883001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-14526014,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-15130126,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-15149774,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-15995201,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-16246086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-16547035,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-2508062,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-2828307,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-3062182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-3130785,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-3294800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-6222285,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-6430698,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-8197122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-8727597,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-9104804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-9184221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17085550-9784364
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
189
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
663-9
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pubmed:dateRevised |
2010-10-19
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pubmed:meshHeading |
pubmed-meshheading:17085550-Bacterial Outer Membrane Proteins,
pubmed-meshheading:17085550-Bacterial Proteins,
pubmed-meshheading:17085550-Base Sequence,
pubmed-meshheading:17085550-DNA Footprinting,
pubmed-meshheading:17085550-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:17085550-Gene Expression Profiling,
pubmed-meshheading:17085550-Gene Expression Regulation, Bacterial,
pubmed-meshheading:17085550-Genes, Bacterial,
pubmed-meshheading:17085550-Iron,
pubmed-meshheading:17085550-Neisseria meningitidis, Serogroup B,
pubmed-meshheading:17085550-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17085550-Oligonucleotides,
pubmed-meshheading:17085550-Protein Binding,
pubmed-meshheading:17085550-Repressor Proteins,
pubmed-meshheading:17085550-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2007
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pubmed:articleTitle |
Expression of the iron-activated nspA and secY genes in Neisseria meningitidis group B by Fur-dependent and -independent mechanisms.
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pubmed:affiliation |
Department of Medicine, Section of Molecular Medicine, Boston University School of Medicine, Boston, MA 02118, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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