|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2006-11-8
|
|
pubmed:abstractText |
The DNA puff BhC4-1 gene of the sciarid Bradysia hygida is induced in salivary glands prior to the pupal molt as a secondary response to the increase in ecdysone titers. Previous studies demonstrated that the BhC4-1 promoter is activated in transgenic Drosophila melanogaster salivary glands as a late response to the ecdysone peak that triggers metamorphosis, revealing that this aspect of BhC4-1 transcriptional regulation is conserved in the Drosophila background. To identify regulators of BhC4-1 expression, we utilized a candidate gene approach and tested the roles of the ecdysone-induced genes BR-C, E74, and E75. Our results reveal that the BR-C Z3 isoform is essential for BhC4-1-lacZ induction in prepupal salivary glands and constitute the first demonstration of the participation of early genes products on DNA puff genes regulation.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Drosophila Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/E74 protein, Drosophila,
http://linkedlifedata.com/resource/pubmed/chemical/E75 protein, insect,
http://linkedlifedata.com/resource/pubmed/chemical/Ecdysterone,
http://linkedlifedata.com/resource/pubmed/chemical/Insect Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Steroid,
http://linkedlifedata.com/resource/pubmed/chemical/Salivary Proteins and Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/broad protein, Drosophila,
http://linkedlifedata.com/resource/pubmed/chemical/puff C4 protein, Bradysia hygida
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1526-954X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
44
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
505-14
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:17083105-Animals,
pubmed-meshheading:17083105-DNA-Binding Proteins,
pubmed-meshheading:17083105-Drosophila,
pubmed-meshheading:17083105-Drosophila Proteins,
pubmed-meshheading:17083105-Ecdysterone,
pubmed-meshheading:17083105-Embryo, Nonmammalian,
pubmed-meshheading:17083105-Gene Expression Regulation, Developmental,
pubmed-meshheading:17083105-Insect Proteins,
pubmed-meshheading:17083105-Mutation,
pubmed-meshheading:17083105-Receptors, Steroid,
pubmed-meshheading:17083105-Salivary Glands,
pubmed-meshheading:17083105-Salivary Proteins and Peptides,
pubmed-meshheading:17083105-Transcription Factors
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Broad-Complex, E74, and E75 early genes control DNA puff BhC4-1 expression in prepupal salivary glands.
|
|
pubmed:affiliation |
Departamento de Biologia Celular e Molecular e de Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
