Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-12-15
pubmed:abstractText
Three new alkaloids (1-3) and twenty-one known compounds were isolated from the stem of Fissistigma oldhamii (Hemsl.) Merr. which was the ruler herb in an approved Traditional Chinese herbal formula used for treatment of rheumatoid arthritis in China and synthesis of one new immunosuppressive alkaloid was achieved. These compounds, including the crude extracts of this herb, exhibited strong activities in the inhibition of T and B cell proliferation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0968-0896
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
988-96
pubmed:meshHeading
pubmed-meshheading:17081761-Animals, pubmed-meshheading:17081761-Annonaceae, pubmed-meshheading:17081761-B-Lymphocytes, pubmed-meshheading:17081761-Cell Proliferation, pubmed-meshheading:17081761-Cyclosporine, pubmed-meshheading:17081761-Dimethyl Sulfoxide, pubmed-meshheading:17081761-Drug Design, pubmed-meshheading:17081761-Immunity, Cellular, pubmed-meshheading:17081761-Immunosuppressive Agents, pubmed-meshheading:17081761-Magnetic Resonance Spectroscopy, pubmed-meshheading:17081761-Mice, pubmed-meshheading:17081761-Mice, Inbred BALB C, pubmed-meshheading:17081761-Plant Bark, pubmed-meshheading:17081761-Plant Extracts, pubmed-meshheading:17081761-Plant Stems, pubmed-meshheading:17081761-Solutions, pubmed-meshheading:17081761-Solvents, pubmed-meshheading:17081761-Spectrophotometry, Infrared, pubmed-meshheading:17081761-Spectrophotometry, Ultraviolet, pubmed-meshheading:17081761-Spleen, pubmed-meshheading:17081761-T-Lymphocytes
pubmed:year
2007
pubmed:articleTitle
Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr.
pubmed:affiliation
Shanghai Research Center for Modernization of Traditional Chinese Medicine and First Department of Pharmacology, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China.
pubmed:publicationType
Journal Article